Siemens Inveon High-Performance Preclinical Imaging System
Michael J. Paulus, PhD, Siemens Molecular Imaging, Molecular Imaging
Abstract: Inveon is a revolutionary preclinical imaging platform, providing integrated small animal PET, SPECT and CT imaging and analysis. Combining cutting-edge technologies with multiple configuration options to fit a broad array of research needs, Inveon is available as a fully integrated or dockable system with single or multimodality configurations. Inveon's exceptional performance is based on true system integration for fast, quantitative analysis with increased sensitivity and resolution. Inveon is built on an innovative new acquisition architecture which unifies data collection from multiple modalities (PET, CT, and SPECT). By providing true system integration and improved system performance, Inveon takes molecular imaging to a new level.

MR-PET: Status quo and Future Perspectives
Arne Hengerer, PhD, Siemens Medical Solutions, Magnetic Resonance
Abstract: Siemens is the first and only company to have shown and published results on the feasibility and development of an MR-PET system. The MR-PET solution is based on MR compatible Avalanche Photodiode Detectors rather than the classic photomultiplier tube. This system enables isocentric and simultaneous measurements without patient repositioning. MRI is not only adding precise anatomical information to PET; there are some unique advantages of an MRI combination (MRI navigator technique for PET, MRI data for PET attenuation correction, excellent soft tissue contrast). Without doubt MRI-PET will be a powerful research engine. However, the technical benefits of MRI-PET have to be translated into an added value for diagnostics, too.
The conceptual design of our first prototypes, some unique technical features and first experimental results will be presented.

High Field Animal MRI for Translational Medicine
Roy E. Gordon, Bruker Biospin MRI, Inc.
Abstract: High-resolution MRI is well suited to image mouse models in order to follow up experimental treatment strategies. Translational research needs imaging capabilities with the same method for both a mouse and a human. Siemens provides the unique capability for translational MRI by means of the syngo-based ClinScan (a Bruker product).
Clinscan ensures easy protocol transfer from and to Clinical scanners. Some applications being developed for the clinical scanners will be available also for ClinScan and vice versa.

High Frequency Ultrasound for Preclinical Imaging
Jim Chomas, Ph. D., Siemens Medical Solutions, Ultrasound
Abstract: Siemens Ultrasound is developing pre-clinical molecular imaging that utilize engineered contrast agent micro bubbles. These acoustic agents are unique in providing low toxicity, rapid clearance, and real-time visualization in pre-clinical imaging. They can be formulated to be retained specifically in diseased tissue and are precisely imaged with high frequency CadenceTM CPS technology on the Siemens Sequoia platform, providing sub-millimeter resolution in real-time. The primary applications being developed by Siemens are non-invasive assessment of inflammation and angiogenesis for screening, diagnosis, and assessment of response to therapy.